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Shandong Gaorui Chemical Co., Ltd.
Tel:86-533-7858337 7858336
Mr zhang:86-15106428713
Mr yu:86-13853323812
Add:Nanshan Industrial Park, Qilu Chemical Industrial Zone, Linyi District, Zibo City, Shandong Province
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Synthesis of Pyrazole Compounds
Pyrazoles are a class of substances with a wide range of biological activities. Our group tested two synthetic routes for the synthesis of acylpyrazoles from hydrazide and acylpyrazoles by acid acylation of the parent pyrazole. A total of 13 new pyrazole compounds were synthesized, all of which passed IR, UV, ~1H NMR. Characterized by means such as EA, the structure was confirmed by single crystal X-Ray diffraction analysis of four compounds. The results show that the acylpyrazole compound obtained by the reaction of the β-diketone and the hydrazide with the parent pyrazole and the acid chloride is an isomer of each other.