Synthesis of novel pyrazolium compounds

The pyrazole compounds have a wide range of biological activities, and many pyrazole group-containing compounds have good herbicidal, insecticidal and bactericidal activities, and because of their high efficiency, low toxicity, and the substituents on the pyrazole ring can be multi-directional. Transformation has been widely used in the field of pesticides, and many pyrazole pesticides have been commercialized in succession. Further research and development of pyrazole derivatives, especially the study of some pyrazole and other heterocyclic compounds, has become one of the hot spots in the pesticide industry today. Terpenoids are important intermediates for the synthesis of heterocyclic rings and are also biologically active compounds. Studies have shown that terpenoids can exhibit antiviral, antitumor and bactericidal activities, and can inhibit many physiological and biochemical processes in the body. . When we synthesized pyridine compounds with different substituents and studied the effect of structural changes on the activity, we tried to introduce the pyrazole ring into the sulfhydryl group, and designed and synthesized two new terpenoids containing pyrazolyl. As the synthon, other heterocyclic compounds linked to the pyrazolyl group can be further synthesized, which is a class of compounds of recent interest in the study of pyrazole derivatives.